ChemicalBook > CAS DataBase List > NSC781406

NSC781406

Product Name
NSC781406
CAS No.
1676893-24-5
Chemical Name
NSC781406
Synonyms
NSC781406;NSC-781406;NSC 781406;NSC781406;NSC-781406;NSC 781406;NSC781406,Phosphoinositide 3-kinase,NSC 781406,NSC-781406,PI3K,Mammalian target of Rapamycin,Inhibitor,inhibit,mTOR;Benzenesulfonamide, 2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-
CBNumber
CB43334188
Molecular Formula
C29H27F2N5O5S2
Formula Weight
627.68
MOL File
1676893-24-5.mol
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NSC781406 Property

Boiling point:
775.1±70.0 °C(Predicted)
Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 10mg/mL; DMSO: 20mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
form 
A solid
pka
6.23±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29226
Product name
NSC 781406
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
29226
Product name
NSC 781406
Packaging
10mg
Price
$261
Updated
2024/03/01
Cayman Chemical
Product number
29226
Product name
NSC 781406
Packaging
5mg
Price
$139
Updated
2024/03/01
ChemScene
Product number
CS-6958
Product name
NSC781406
Purity
99.91%
Packaging
10mg
Price
$200
Updated
2021/12/16
AK Scientific
Product number
5398EJ
Product name
2,4-Difluoro-N-[2-methoxy-5-[4-[3-(4-methylsulfonylpiperazin-1-yl)prop-1-ynyl]quinolin-6-yl]pyridin-3-yl]benzenesulfonamide
Packaging
5mg
Price
$252
Updated
2021/12/16
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NSC781406 Chemical Properties,Usage,Production

Description

NSC 781406 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR; IC50s = 2.0, 9.4, 2.7, 14, and 5.4 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR, respectively). It inhibits cell growth in the NCI-60 panel of cancer cell lines (mean GI50 = 65 nM). NSC 781406 (30 mg/kg) reduces tumor volume in a BEL-7404 hepatic cancer mouse xenograft model.

NSC781406 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC781406 Suppliers

China 27 United States 6 USA 1 Global 34
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58

1676893-24-5, NSC781406Related Search:

CP671305 5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE 4-Chloro-N,N-diethylbenzaMide, 97% 4-Chloro-N,N-di-n-propylbenzaMide, 97% TIMTEC-BB SBB006342 2,4-Thiazolidinedione,5-[(4-hydroxy-3-methoxyphenyl)methylene]- 4-Chloro-N,N-diisopropylbenzamide Pifithrin-μ 2-Pyridinecarbothioamide, N-2-pyridinyl- 1,3-Bis(4-aminophenyl)urea 5-(4-iodobenzylidene)rhodanine S3I-201 NSC228155 NSC632839hydrochloride NSC23005 Sodium HAMNO NSC 247030 NSC 42834

  • NSC781406
  • NSC781406;NSC-781406;NSC 781406
  • NSC-781406;NSC 781406
  • Benzenesulfonamide, 2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-
  • NSC781406,Phosphoinositide 3-kinase,NSC 781406,NSC-781406,PI3K,Mammalian target of Rapamycin,Inhibitor,inhibit,mTOR
  • 1676893-24-5
  • C29H27F2N5O5S2